SCHEMBL2187378

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2188257	0.89	HIF1A (0.50)	PPARAHDAC1MAPTFFAR1NAMPT
	SCHEMBL2188031	0.89	HIF1A (0.50)	PPARAHDAC1MAPTFFAR1NAMPT
	SCHEMBL2186694	0.79	EGFR (0.50)	PPARAHDAC1MAPTFFAR1STING1
	SCHEMBL2186903	0.79	PPARA (0.59)	PPARAHDAC1MAPTSCDMEN1
	SCHEMBL2188951	0.76	HIF1A (0.44)	PPARAFFAR1NAMPTFNTAFNTB
	SCHEMBL11250263	0.74	MAPT (0.57)	PPARAHDAC1MAPTFFAR1RAB9A
	SCHEMBL15668111	0.73	EGFR (0.67)	PPARAHDAC1MAPTFFAR1STING1
	SCHEMBL25762484	0.72	TRPA1 (0.56)	KCNA3CNR1RAB9AMEN1KMT2A
	SCHEMBL11242577	0.72	FFAR1 (0.50)	PPARAHDAC1MAPTFFAR1STING1
	SCHEMBL7137660	0.72	CES2 (0.55)	KCNA3RAB9AGAAANO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.