Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16767096 | 0.85 | CSNK1E (0.53) | IRAK4L3MBTL1 | |
| SCHEMBL2187668 | 0.75 | KMT2A (0.48) | L3MBTL1 | |
| SCHEMBL2187276 | 0.73 | GSK3B (0.46) | IRAK4TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL22811380 | 0.71 | L3MBTL1 (0.55) | IRAK4L3MBTL1 | |
| SCHEMBL27735961 | 0.71 | HTT (0.48) | IRAK4TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2187686 | 0.71 | SMN1; SMN2 (0.46) | L3MBTL1 | |
| SCHEMBL27756403 | 0.70 | IRAK4 (0.56) | IRAK4TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL18619678 | 0.70 | LMNA (0.55) | IRAK4L3MBTL1 | |
| SCHEMBL3068984 | 0.70 | NPC1 (0.55) | IRAK4L3MBTL1 | |
| SCHEMBL15348570 | 0.69 | HRH3 (0.53) | IRAK4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343293-A1 | NOVEL PIPERIDIN-4-YL-THIAZOLE-CARBOXAMIDE ANALOGUES AS INHIBITORS OF T-CELL PROLIFERATION AND USES THEREOF | 4SC AG (DE) | 2011-07-13 | — | — | EP | disclosed |