Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 13/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.40 |
| ▸ | GMPS | P49915 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21874995 | 0.79 | CDK1 (0.42) | ADORA3ADORA2AADORA1TP53SLC29A1 | |
| SCHEMBL21874997 | 0.79 | PAX8 (0.42) | ADORA3ADORA2AADORA1GMPSPAX8 | |
| SCHEMBL21875003 | 0.77 | CCNB2 (0.49) | ADORA3ADORA2AADORA1PAX8ADORA2B | |
| SCHEMBL2298662 | 0.74 | GMPS (0.63) | ADORA3ADORA2AGMPSADORA2B | |
| SCHEMBL19583138 | 0.73 | SLC29A1 (0.64) | ADORA3TP53SLC29A1PAX8SMN1; SMN2 | |
| SCHEMBL15570013 | 0.72 | KDM4E (0.45) | ADORA3TP53SLC29A1SMN1; SMN2LMNA | |
| SCHEMBL19583070 | 0.70 | SLC29A1 (0.72) | ADORA3ADORA2AADORA1TP53SLC29A1 | |
| SCHEMBL17825994 | 0.70 | SLC29A1 (0.72) | ADORA3ADORA2AADORA1TP53SLC29A1 | |
| SCHEMBL25425994 | 0.69 | GMPS (0.35) | ADORA3ADORA1GMPSSLC29A1 | |
| SCHEMBL4575806 | 0.69 | GMPS (0.35) | ADORA3ADORA1GMPSSLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3229772-B1 | 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF | UNIV PALACKEHO (CZ) | 2020-04-29 | — | — | EP | disclosed |