Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 2/20 | 0.49 |
| ▸ | CDK1 | P06493 | 2/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.49 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21874995 | 0.82 | CDK1 (0.42) | CDK1ADORA3ADORA2AADORA1 | |
| SCHEMBL21874997 | 0.78 | PAX8 (0.42) | CCNB2CDK1CCNB1CCNB3ADORA3 | |
| SCHEMBL21875000 | 0.77 | ADORA3 (0.40) | ADORA3PAX8ADORA2AADORA1ADORA2B | |
| SCHEMBL19582969 | 0.75 | SLC29A1 (0.67) | ADORA3PAX8ADORA2AADORA1 | |
| SCHEMBL14713290 | 0.72 | ADORA3 (0.75) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL638246 | 0.72 | ADORA3 (0.75) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL638245 | 0.72 | ADORA3 (0.75) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL20626312 | 0.72 | ADORA3 (0.75) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL20626310 | 0.72 | ADORA3 (0.75) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL17825947 | 0.72 | ADORA3 (0.75) | ADORA3ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3229772-B1 | 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF | UNIV PALACKEHO (CZ) | 2020-04-29 | — | — | EP | disclosed |