Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.40 |
| ▸ | CDK1 | P06493 | 3/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.40 |
| ▸ | GMPS | P49915 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21875000 | 0.79 | ADORA3 (0.40) | PAX8ADORA3ADORA2AGMPSADORA1 | |
| SCHEMBL21874995 | 0.79 | CDK1 (0.42) | CDK1ADORA3ADORA2AADORA1 | |
| SCHEMBL21875003 | 0.78 | CCNB2 (0.49) | PAX8CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL19583021 | 0.73 | SLC29A1 (0.63) | PAX8PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL2298662 | 0.73 | GMPS (0.63) | ADORA3ADORA2AGMPSADORA2B | |
| SCHEMBL17825930 | 0.71 | PAX8 (0.80) | PAX8ADORA3ADORA2APRKAG1PRKAA1 | |
| SCHEMBL17824404 | 0.71 | PAX8 (0.80) | PAX8ADORA3ADORA2APRKAG1PRKAA1 | |
| SCHEMBL640682 | 0.70 | CDK1 (0.51) | PAX8CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL15570013 | 0.70 | KDM4E (0.45) | CDK1ADORA3 | |
| SCHEMBL25425994 | 0.68 | GMPS (0.35) | ADORA3GMPSADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3229772-B1 | 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF | UNIV PALACKEHO (CZ) | 2020-04-29 | — | — | EP | disclosed |