Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.42 |
| ▸ | SLC29A1 | Q99808 | 5/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | CDK7 | P50613 | 1/20 | 0.41 |
| ▸ | CCNH | P51946 | 1/20 | 0.41 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21875003 | 0.82 | CCNB2 (0.49) | CDK1ADORA3ADORA2AADORA1 | |
| SCHEMBL21875000 | 0.79 | ADORA3 (0.40) | ADORA3ADORA2ASLC29A1TP53TDP1 | |
| SCHEMBL21874997 | 0.79 | PAX8 (0.42) | CDK1ADORA3ADORA2AADORA1 | |
| SCHEMBL15570013 | 0.76 | KDM4E (0.45) | CDK1ADORA3SLC29A1MAPK1TP53 | |
| SCHEMBL2298662 | 0.73 | GMPS (0.63) | ADORA3ADORA2A | |
| SCHEMBL641098 | 0.71 | SLC29A1 (0.78) | ADORA3ADORA2ASLC29A1TP53TDP1 | |
| SCHEMBL19583088 | 0.71 | SLC29A1 (0.78) | ADORA3ADORA2ASLC29A1TP53TDP1 | |
| SCHEMBL17825954 | 0.71 | SLC29A1 (0.78) | ADORA3ADORA2ASLC29A1TP53TDP1 | |
| SCHEMBL20626311 | 0.71 | SLC29A1 (0.78) | ADORA3ADORA2ASLC29A1TP53TDP1 | |
| SCHEMBL20626314 | 0.71 | SLC29A1 (0.78) | ADORA3ADORA2ASLC29A1TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3229772-B1 | 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF | UNIV PALACKEHO (CZ) | 2020-04-29 | — | — | EP | disclosed |