Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2188506 | 0.82 | L3MBTL1 (0.45) | KDM4EL3MBTL1KMT2AALDH1A1GAA | |
| SCHEMBL2187822 | 0.81 | KDM4E (0.61) | KDM4EL3MBTL1KMT2AALDH1A1GAA | |
| SCHEMBL2185749 | 0.78 | ALDH1A1 (0.60) | KDM4EL3MBTL1KMT2AALDH1A1GAA | |
| SCHEMBL4613771 | 0.78 | KMT2A (0.47) | KDM4EL3MBTL1KMT2AALDH1A1GAA | |
| SCHEMBL2187940 | 0.76 | KMT2A (0.45) | L3MBTL1KMT2AALDH1A1GAAHPGD | |
| SCHEMBL2188707 | 0.73 | ALDH1A1 (0.42) | KDM4EL3MBTL1KMT2AALDH1A1GAA | |
| SCHEMBL2188417 | 0.73 | ALDH1A1 (0.43) | KDM4EL3MBTL1KMT2AALDH1A1GAA | |
| SCHEMBL4100554 | 0.72 | KMT2A (0.56) | KDM4EL3MBTL1KMT2AALDH1A1GAA | |
| SCHEMBL2188574 | 0.71 | INPPL1 (0.45) | KDM4EL3MBTL1KMT2AALDH1A1GAA | |
| SCHEMBL4101815 | 0.68 | MEN1 (0.58) | KDM4EL3MBTL1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578741-B1 | AROMATIC COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2011-07-13 | — | — | EP | claimed |