Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2185749 | 0.85 | ALDH1A1 (0.60) | L3MBTL1ALDH1A1HPGDGAAKDM4E | |
| SCHEMBL2188707 | 0.85 | ALDH1A1 (0.42) | L3MBTL1NPSR1ALDH1A1HPGDGAA | |
| SCHEMBL2187828 | 0.82 | KDM4E (0.39) | L3MBTL1ALDH1A1HPGDGAAKDM4E | |
| SCHEMBL2187940 | 0.80 | KMT2A (0.45) | L3MBTL1ALDH1A1HPGDGAAKMT2A | |
| SCHEMBL2188417 | 0.80 | ALDH1A1 (0.43) | L3MBTL1ALDH1A1HPGDGAAKDM4E | |
| SCHEMBL2187525 | 0.78 | HPGD (0.72) | L3MBTL1NPSR1ALDH1A1HPGDGAA | |
| SCHEMBL2188574 | 0.75 | INPPL1 (0.45) | L3MBTL1ALDH1A1HPGDGAAKDM4E | |
| SCHEMBL2186717 | 0.71 | MAPT (0.52) | L3MBTL1NPSR1ALDH1A1HPGDGAA | |
| SCHEMBL2188985 | 0.69 | KMT2A (0.39) | L3MBTL1ALDH1A1HPGDKMT2ARAB9A | |
| SCHEMBL2186838 | 0.68 | MEN1 (0.63) | L3MBTL1NPSR1ALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578741-B1 | AROMATIC COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2011-07-13 | — | — | EP | claimed |