Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28315993 | 0.76 | SLC7A5 (0.41) | SLC7A5 | |
| SCHEMBL29027401 | 0.75 | SLC7A5 (0.39) | SLC7A5 | |
| SCHEMBL17268516 | 0.74 | TSHR (0.44) | — | |
| SCHEMBL5987142 | 0.72 | TSHR (0.42) | SLC7A5 | |
| SCHEMBL7603101 | 0.72 | TSHR (0.42) | SLC7A5 | |
| SCHEMBL5986125 | 0.72 | TSHR (0.42) | SLC7A5 | |
| SCHEMBL17268547 | 0.71 | CYP3A4 (0.39) | — | |
| SCHEMBL4418153 | 0.71 | LMNA (0.34) | — | |
| SCHEMBL769573 | 0.71 | SLC7A5 (0.48) | SLC7A5 | |
| SCHEMBL769572 | 0.71 | SLC7A5 (0.48) | SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9085508-B2 | Nitric oxide releasing amino acid ester compound, composition and method of use | ORAL DELIVERY TECHNOLOGY LTD. (US) | 2015-07-21 | — | — | US | disclosed |
| US-9085528-B2 | Nitric oxide amino acid ester compound, composition for increasing nitric oxide levels and method of use | ORAL DELIVERY TECHNOLOGY LTD. (US) | 2015-07-21 | — | — | US | disclosed |
| EP-2342175-B1 | NITRIC OXIDE RELEASING AMINO ACID ESTER COMPOUND, COMPOSITION AND METHOD OF USE | NITROGENIX INC (VG) | 2015-05-27 | — | — | EP | disclosed |
| US-20140057873-A1 | NITRIC OXIDE RELEASING AMINO ACID ESTER COMPOUND, COMPOSITION AND METHOD OF USE | FARBER MICHAEL (US) | 2014-02-27 | — | — | US | disclosed |
| US-20110195935-A1 | NITRIC OXIDE RELEASING AMINO ACID ESTER COMPOUND, COMPOSITION AND METHOD OF USE | BENOIT & COTE (CA) | 2011-08-11 | — | — | US | disclosed |
| EP-2342175-A1 | NITRIC OXIDE RELEASING AMINO ACID ESTER COMPOUND, COMPOSITION AND METHOD OF USE | Nitrogenix Inc. (VG) | 2011-07-13 | — | — | EP | disclosed |
| US-20100311780-A1 | Nitric oxide amino acid ester compound, composition for increasing nitirc oxide levels and method of use | ORAL DELIVERY TECHNOLOGY LTD. (CA) | 2010-12-09 | — | — | US | disclosed |
| US-7807716-B2 | Nitric oxide amino acid ester compound, compositions for increasing nitric oxide levels and method of use | ORAL DELIVERY TECHNOLOGY LTD. (CA) | 2010-10-05 | — | — | US | disclosed |
| WO-2010034118-A1 | NITRIC OXIDE RELEASING AMINO ACID ESTER COMPOUND, COMPOSITION AND METHOD OF USE | ORAL DELIVERY TECHNOLOGY LTD. (CA) | 2010-04-01 | — | — | WO | disclosed |
| US-20100076043-A1 | NITRIC OXIDE AMINO ACID ESTER COMPOUND, COMPOSITIONS FOR INCREASING NITRIC OXIDE LEVELS AND METHOD OF USE | ORAL DELIVERY TECHNOLOGY LTD. (CA) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076043-A1 | NITRIC OXIDE AMINO ACID ESTER COMPOUND, COMPOSITIONS FOR INCREASING NITRIC OXIDE LEVELS AND METHOD OF USE | NOS1, NOS2, NOS3 | SLC7A5 97/4885 |
| US-20110195935-A1 | NITRIC OXIDE RELEASING AMINO ACID ESTER COMPOUND, COMPOSITION AND METHOD OF USE | NOS2, NOS3, NOS1 | SLC7A5 89/4885 |
| US-20100311780-A1 | Nitric oxide amino acid ester compound, composition for increasing nitirc oxide levels and method of use | NOS1, NOS2, NOS3 | SLC7A5 60/4885 |
| US-20140057873-A1 | NITRIC OXIDE RELEASING AMINO ACID ESTER COMPOUND, COMPOSITION AND METHOD OF USE | NOS2, NOS3, NOS1 | SLC7A5 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.