SCHEMBL21879356

SCHEMBL21879356

CC(C)[C@H](NC(=O)C(N)CCCCN)C(N)=O

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DPP8 Q6V1X1 6/20 0.51
DPP9 Q86TI2 6/20 0.51
DPP7 Q9UHL4 6/20 0.51
GNAI3 P08754 1/20 0.48
GNAO1 P09471 1/20 0.48
GNAI1 P63096 1/20 0.48
GSR P00390 1/20 0.46
DPP4 P27487 3/20 0.46
SLC15A1 P46059 1/20 0.39
MMP2 P08253 1/20 0.39
FURIN P09958 1/20 0.38
TLR2 O60603 2/20 0.38
ERAP2 Q6P179 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22612668 0.87 GSR (0.55) DPP8DPP9DPP7GNAI3GNAO1
SCHEMBL28000252 0.87 GSR (0.55) DPP8DPP9DPP7GNAI3GNAO1
SCHEMBL120692 0.87 DPP8 (0.51) DPP8DPP9DPP7GNAI3GNAO1
SCHEMBL31722025 0.87 GSR (0.55) DPP8DPP9DPP7GNAI3GNAO1
SCHEMBL14906253 0.87 GSR (0.55) DPP8DPP9DPP7GNAI3GNAO1
SCHEMBL11111915 0.87 DPP8 (0.43) DPP8DPP9DPP7GNAI3GNAO1
SCHEMBL31126783 0.87 DPP8 (0.46) DPP8DPP9DPP7GNAI3GNAO1
SCHEMBL11111912 0.86 FOLH1 (0.48) DPP8DPP9DPP7DPP4FURIN
SCHEMBL11102541 0.86 FURIN (0.42) DPP8DPP9DPP7FURIN
SCHEMBL27759901 0.85 SLC15A1 (0.56) DPP8DPP9DPP7GNAI3GNAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10611824-B2 Solid phase TGase-mediated conjugation of antibodies INNATE PHARMA (FR) 2020-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10611824-B2 Solid phase TGase-mediated conjugation of antibodies TGM3, TGM2, TGM6 DPP8 412/4885DPP9 250/4885DPP7 683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.