SCHEMBL21879645

SCHEMBL21879645

[c]1cc2sc3ccccc3c2cc1-c1cccnc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
CYP11B1 P15538 3/20 0.40
GPR3 P46089 1/20 0.39
DYRK1A Q13627 2/20 0.39
DYRK1B Q9Y463 1/20 0.39
CYP2A6 P11509 5/20 0.38
CYP3A4 P08684 3/20 0.38
ALDH1A1 P00352 3/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 2/20 0.36
CYP2B6 P20813 2/20 0.36
CYP2C19 P33261 2/20 0.36
IDO1 P14902 1/20 0.36
LRRK2 Q5S007 1/20 0.36
GBA1 P04062 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CYP19A1 P11511 2/20 0.36
CYP11B2 P19099 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28575112 0.84 GPR3 (0.42) NPC1RAB9AGPR3ALDH1A1CYP1A2
SCHEMBL21879689 0.84 GPR3 (0.48) RAB9AGPR3ALDH1A1CYP1A2KDM4E
SCHEMBL22780062 0.78 CYP11B1 (0.51) NPC1RAB9ACYP11B1GPR3DYRK1A
SCHEMBL21295743 0.75 DYRK1A (0.42) NPC1RAB9ACYP11B1DYRK1ADYRK1B
SCHEMBL28570307 0.74 GABRA1 (0.44) NPC1RAB9AGPR3ALDH1A1CYP1A2
SCHEMBL21295683 0.73 NPC1 (0.42) NPC1RAB9ACYP11B1GPR3DYRK1A
SCHEMBL21295951 0.72 GPR3 (0.42) NPC1RAB9AGPR3CYP3A4ALDH1A1
SCHEMBL21296035 0.71 CYP2A6 (0.45) NPC1RAB9ACYP11B1DYRK1ADYRK1B
SCHEMBL21879710 0.70 CYP11B1 (0.44) NPC1RAB9ACYP11B1DYRK1ADYRK1B
SCHEMBL19166781 0.70 CYP11B1 (0.47) NPC1RAB9ACYP11B1CYP2A6CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed