SCHEMBL28575112

SCHEMBL28575112

[c]1cc2sc3ccccc3c2cc1-c1ccncc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.42
RAB9A P51151 3/20 0.37
KDM4E B2RXH2 2/20 0.37
NPC1 O15118 2/20 0.37
MAPT P10636 6/20 0.37
ALDH1A1 P00352 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
HPGD P15428 2/20 0.37
PTGIR P43119 1/20 0.35
NOTUM Q6P988 1/20 0.33
TDP1 Q9NUW8 2/20 0.33
MEN1 O00255 1/20 0.33
CCR6 P51684 1/20 0.33
KMT2A Q03164 1/20 0.33
HIF1A Q16665 1/20 0.33
POLB P06746 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ROCK1 Q13464 1/20 0.33
HSP90AA1 P07900 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21295951 0.88 GPR3 (0.42) GPR3RAB9AKDM4ENPC1MAPT
SCHEMBL21879689 0.87 GPR3 (0.48) GPR3RAB9AKDM4EMAPTALDH1A1
SCHEMBL21879645 0.84 NPC1 (0.41) GPR3RAB9AKDM4ENPC1MAPT
SCHEMBL28570307 0.78 GABRA1 (0.44) GPR3RAB9AKDM4ENPC1MAPT
SCHEMBL28304152 0.72 RAB9A (0.50) GPR3RAB9AKDM4ENPC1MAPT
SCHEMBL26813480 0.72 GPR3 (0.45) GPR3RAB9AKDM4ENPC1MAPT
SCHEMBL28573918 0.70 GPR3 (0.52) GPR3RAB9AKDM4ENPC1MAPT
SCHEMBL8964456 0.70 GPR3 (0.52) GPR3RAB9AKDM4ENPC1MAPT
SCHEMBL21300530 0.70 MAPT (0.40) RAB9AKDM4ENPC1MAPTALDH1A1
Dibenzothiophene SCHEMBL28647613 0.68 GPR3 (0.67) GPR3RAB9AKDM4ENPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed