Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724968 | 0.85 | KMT2A (0.65) | RAB9ANPC1KMT2AALDH1A1MAPT | |
| SCHEMBL27877588 | 0.85 | RAB9A (0.67) | RAB9AUSP2TSHRLMNACRHBP | |
| SCHEMBL21880164 | 0.85 | RAB9A (0.67) | RAB9AUSP2TSHRLMNACRHBP | |
| SCHEMBL21880165 | 0.85 | RAB9A (0.67) | RAB9AUSP2TSHRLMNACRHBP | |
| SCHEMBL30453904 | 0.85 | RAB9A (0.67) | RAB9AUSP2TSHRLMNACRHBP | |
| SCHEMBL9724805 | 0.82 | RAB9A (0.65) | RAB9AUSP2TSHRLMNACRHBP | |
| SCHEMBL9724808 | 0.82 | MEN1 (0.53) | RAB9ALMNANPC1MAPK1KMT2A | |
| SCHEMBL9724967 | 0.81 | MAPT (0.67) | RAB9ATSHRLMNANPC1KMT2A | |
| SCHEMBL9724970 | 0.81 | MAPT (0.55) | RAB9ALMNANPC1NLRP3MAPK1 | |
| SCHEMBL9724786 | 0.80 | DDX3X (0.51) | RAB9ALMNAKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | disclosed |