SCHEMBL2188104

SCHEMBL2188104

O=C(O)c1cccc(-c2ccc(C(=O)O)c(C(=O)OC(=O)c3cc(-c4cccc(C(=O)O)c4)ccc3C(=O)O)c2)c1

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMO O15229 2/20 0.56
PTPN11 Q06124 1/20 0.52
LMNA P02545 1/20 0.51
GAA P10253 1/20 0.51
RXRA P19793 2/20 0.50
RXRB P28702 2/20 0.50
ERN1 O75460 1/20 0.48
KDM4E B2RXH2 1/20 0.47
ACMSD Q8TDX5 3/20 0.46
DDT P30046 1/20 0.46
HNF4A P41235 2/20 0.45
MCL1 Q07820 2/20 0.45
DHFR P00374 1/20 0.45
FOLH1 Q04609 1/20 0.44
KEAP1 Q14145 1/20 0.44
DCLRE1A Q6PJP8 1/20 0.44
DCLRE1B Q9H816 1/20 0.44
MYC P01106 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465422 0.88 KMO (0.66) KMOPTPN11LMNAGAARXRA
Water SCHEMBL21878438 0.86 KMO (0.63) KMOPTPN11LMNAGAARXRA
SCHEMBL629105 0.86 ACMSD (0.59) KDM4EACMSDHNF4AMCL1DHFR
SCHEMBL942689 0.85 PTPN11 (0.48) PTPN11LMNARXRARXRBERN1
SCHEMBL168300 0.84 KMT2A (0.50) RXRARXRBKDM4EACMSDHNF4A
SCHEMBL21173955 0.83 KMO (0.68) KMOLMNAGAARXRARXRB
SCHEMBL3474963 0.82 KDM4E (0.57) KMOLMNAKDM4EMYC
SCHEMBL714874 0.81 KMT2A (0.50) RXRARXRBKDM4EACMSDHNF4A
SCHEMBL2174840 0.81 KDM4E (0.60) LMNAKDM4EMYC
Isophthalic Acid SCHEMBL19579513 0.81 KDM4E (0.56) LMNAKDM4EMYC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8449200-B2 Resin composition for sliding member and rolling bearing NTN CORPORATION (JP) 2013-05-28 US disclosed
US-8182155-B2 Lubricating grease and lubricating grease-enclosed roller bearing NTN CORPORATION (JP) 2012-05-22 US disclosed
US-7973122-B2 Polyamideimide compositions having multifunctional core structures GENERAL CABLE TECHNOLOGIES CORPORATION (US) 2011-07-05 US disclosed
US-20100142872-A1 RESIN COMPOSITION FOR SLIDING MEMBER AND ROLLING BEARING NTN CORPORATION (JP) 2010-06-10 US disclosed
EP-2157135-A1 RESIN COMPOSITION FOR SLIDE MEMBER AND ROLLER BEARING NTN Corporation (JP) 2010-02-24 EP disclosed
US-20090232432-A1 Lubricating grease and lubricating grease-enclosed roller bearing NTN CORPORATION (JP) 2009-09-17 US disclosed
EP-1956072-A1 LUBRICATING GREASE AND LUBRICATING-GREASE-FILLED ROLLER BEARING NTN CORPORATION (JP) 2008-08-13 EP disclosed
US-20080160304-A1 Polyamideimide compositions having multifunctional core structures GENERAL CABLE TECHNOLOGIES 2008-07-03 US disclosed
US-20050282010-A1 Polyamideimide compositions having multifunctional core structures GENERAL CABLE TECHNOLOGIES CORPORATION 2005-12-22 US disclosed
US-5840802-A HEAT RESISTANCE AND IMPACT STRENGTH FOR THERMOPLASTIC RESINS GENERAL ELECTRIC COMPANY (US) 1998-11-24 US disclosed
US-5306785-A Molding materials GENERAL ELECTRIC COMPANY (US) 1994-04-26 US disclosed
EP-0586181-A2 Thermoplastic polyester elastomer resin compositions GE PLASTICS JAPAN LIMITED (JP) 1994-03-09 EP disclosed
EP-0322778-B1 BICOMPONENT MOISTURE BARRIER POLY(ETHERIMIDE) ESTER FILMS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-09-08 EP disclosed
EP-0537014-A2 Dual graft stage and thermally stabilized polyorganisiloxane/polyvinyl-based graft copolymers and thermoplastic compositions containing the same GENERAL ELECTRIC COMPANY (US) 1993-04-14 EP disclosed
EP-0322777-B1 VAPOR PERMEABLE POLY(ETHERIMIDE) ESTER ELASTOMER FILMS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-11-04 EP disclosed
EP-0322777-A1 Vapor permeable poly(etherimide) ester elastomer films E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-07-05 EP disclosed
EP-0322778-A2 Bicomponent moisture barrier poly(etherimide) ester films E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-07-05 EP disclosed
US-4769273-A HAVING DIFFERENTIAL TRANSFER OF WATER VAPOR TO PREVENT BUILD-UP; TEXTILE COVERING; SURGICAL DRAPES; WATERPROOFED CLOTHING E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-09-06 US disclosed