Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18744853 | 0.77 | L3MBTL1 (0.41) | LMNACHRM2CHRM1CHRM3SMN1; SMN2 | |
| SCHEMBL27589900 | 0.73 | CHRM2 (0.43) | LMNACHRM2CHRM1CHRM3SMN1; SMN2 | |
| SCHEMBL27410746 | 0.72 | CHRM2 (0.44) | LMNACHRM2CHRM1CHRM3SMN1; SMN2 | |
| SCHEMBL20749199 | 0.72 | KMT2A (0.38) | LMNACHRM2CHRM1CHRM3SMN1; SMN2 | |
| SCHEMBL155984 | 0.70 | ALDH1A1 (0.54) | LMNASMN1; SMN2ALDH1A1CYP3A4PPARA | |
| SCHEMBL104518 | 0.70 | ALDH1A1 (0.54) | LMNASMN1; SMN2ALDH1A1CYP3A4PPARA | |
| SCHEMBL103235 | 0.70 | ALDH1A1 (0.54) | LMNASMN1; SMN2ALDH1A1CYP3A4PPARA | |
| SCHEMBL8400939 | 0.69 | SRC (0.54) | LMNAALDH1A1CYP3A4PPARACYP2D6 | |
| SCHEMBL14556742 | 0.69 | CHRM2 (0.41) | LMNACHRM2CHRM1CHRM3SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL38660904 | 0.69 | ALDH1A1 (0.53) | LMNASMN1; SMN2ALDH1A1CYP3A4PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11021445-B2 | Carboxylic acid derivative as AT2R receptor antagonist | SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2021-06-01 | — | — | US | disclosed |
| EP-3620454-B1 | CARBOXYLIC ACID DERIVATIVE AS AT2R RECEPTOR ANTAGONIST | SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2021-05-05 | — | — | EP | disclosed |
| US-20200102275-A1 | CARBOXYLIC ACID DERIVATIVE AS AT2R RECEPTOR ANTAGONIST | SHANDONG DANHONG PHARMACEUTICAL CO., LTD. | 2020-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200102275-A1 | CARBOXYLIC ACID DERIVATIVE AS AT2R RECEPTOR ANTAGONIST | AGTR2, AGTR1, HCAR2 | LMNA 4457/4885CHRM2 262/4885CHRM1 784/4885 |
| US-11021445-B2 | Carboxylic acid derivative as AT2R receptor antagonist | AGTR2, AGTR1, HCAR2 | LMNA 4457/4885CHRM2 262/4885CHRM1 784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.