Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19449766 | 0.87 | MAPT (0.39) | MAPTSMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL19449652 | 0.83 | MAPT (0.53) | MAPTSMN1; SMN2ALDH1A1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL17560743 | 0.81 | MAPT (0.52) | MAPTSMN1; SMN2ALDH1A1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL17560755 | 0.79 | SMN1; SMN2 (0.55) | MAPTSMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL19449854 | 0.78 | MAPT (0.39) | MAPTSMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL21882655 | 0.77 | ALDH1A1 (0.53) | MAPTSMN1; SMN2ALDH1A1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL17560981 | 0.77 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2ALDH1A1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL17560938 | 0.76 | LMNA (0.41) | MAPTSMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL21882656 | 0.75 | ALDH1A1 (0.52) | MAPTSMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL17560954 | 0.71 | MAPT (0.51) | MAPTSMN1; SMN2ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200102287-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2020-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200102287-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | DPM1, ABCB11, PIGS | MAPT 3694/4885SMN1; SMN2 3002/4885ALDH1A1 840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.