Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 9/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.57 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.56 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27898271 | 0.90 | OPRD1 (0.61) | OPRD1OPRM1OPRK1 | |
| SCHEMBL31736791 | 0.89 | OPRK1 (0.57) | OPRD1OPRM1OPRK1 | |
| SCHEMBL24152321 | 0.86 | MMP2 (0.54) | OPRD1OPRM1OPRK1 | |
| SCHEMBL29871918 | 0.86 | NPY4R (0.66) | OPRD1OPRM1OPRK1KISS1R | |
| SCHEMBL31433318 | 0.85 | OPRD1 (0.58) | OPRD1OPRM1OPRK1CTSB | |
| SCHEMBL18176630 | 0.84 | KISS1R (0.62) | OPRD1OPRM1OPRK1KISS1R | |
| SCHEMBL21886335 | 0.84 | KISS1R (0.62) | OPRD1OPRM1OPRK1KISS1R | |
| SCHEMBL11931977 | 0.84 | KISS1R (0.62) | OPRD1OPRM1OPRK1KISS1R | |
| SCHEMBL19249634 | 0.84 | KISS1R (0.62) | OPRD1OPRM1OPRK1KISS1R | |
| SCHEMBL29568724 | 0.84 | OPRK1 (0.59) | OPRD1OPRM1OPRK1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020056249-A1 | ORAL FORMULATIONS OF KAPPA OPIOID RECEPTOR AGONISTS | CARA THERAPEUTICS, INC. (US) | 2020-03-19 | — | — | WO | disclosed |