Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21474585 | 0.83 | HSD11B1 (0.42) | APLNRHSD11B1 | |
| SCHEMBL21474584 | 0.77 | HSD11B1 (0.43) | APLNRHSD11B1 | |
| SCHEMBL19933348 | 0.77 | HSD11B1 (0.39) | APLNRHSD11B1 | |
| SCHEMBL8933185 | 0.74 | APLNR (0.44) | APLNRHSD11B1 | |
| SCHEMBL11285851 | 0.73 | — | — | |
| SCHEMBL23457777 | 0.72 | APLNR (0.43) | APLNRHSD11B1 | |
| SCHEMBL715584 | 0.72 | APLNR (0.43) | APLNRHSD11B1 | |
| SCHEMBL30879578 | 0.72 | APLNR (0.43) | APLNRHSD11B1 | |
| SCHEMBL4600499 | 0.72 | APLNR (0.60) | APLNRHSD11B1 | |
| SCHEMBL19121536 | 0.71 | HSD11B1 (0.35) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2736885-B1 | QUINOLINE-, QUINOXALINE OR BENZOTHIAZOLE BASED CYSTEINYL LEUKOTRIENE ANTAGONISTS (LTC4) | SUN PHARMA ADVANCED RES CO LTD (IN) | 2020-03-25 | — | — | EP | disclosed |