SCHEMBL21883580

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24971842	0.86	HPGD (0.47)	HPGDHSD17B10HIF1ASMN1; SMN2CASP7
	SCHEMBL23492884	0.81	ESR1 (0.33)	HTTMEN1KMT2ARECQLPOLB
	SCHEMBL19116110	0.73	GAA (0.36)	HPGDHSD17B10HIF1ASMN1; SMN2CASP7
	SCHEMBL1548068	0.73	CA1 (0.33)	ESR1
	SCHEMBL18691189	0.72	HPGD (0.50)	HPGDHSD17B10HIF1ASMN1; SMN2CASP7
	SCHEMBL20621268	0.72	HSD17B10 (0.41)	HPGDHSD17B10HIF1ASMN1; SMN2CASP7
	SCHEMBL8726286	0.72	ADRA2A (0.36)	HSD17B10HTTMEN1KMT2ACYP3A4
	SCHEMBL21883544	0.72	TRPV4 (0.36)	ESR1ARESR2TTR
	SCHEMBL24870543	0.69	KDM4E (0.33)	HPGDHSD17B10HIF1ASMN1; SMN2CASP7
	SCHEMBL20254645	0.69	MEN1 (0.40)	HPGDSMN1; SMN2TSHRCYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.