SCHEMBL21885053

SCHEMBL21885053

c1ccc(-c2ccc(N(c3ccncc3)c3cccc(-c4ccc(-c5ccc6c(c5)c5ccccc5n5c7ccccc7c(-c7ccccc7)c65)cc4)c3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.38
MKNK1 Q9BUB5 1/20 0.36
MAPK14 Q16539 3/20 0.35
IMPDH2 P12268 1/20 0.34
TSPO P30536 1/20 0.33
HSD17B1 P14061 1/20 0.33
HSD17B2 P37059 1/20 0.33
PIK3CA P42336 1/20 0.33
CHEK1 O14757 2/20 0.32
CYP17A1 P05093 1/20 0.31
NPY5R Q15761 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21885094 0.96 SLC6A2 (0.38) SLC6A2MKNK1MAPK14IMPDH2TSPO
SCHEMBL21885028 0.96 SLC6A2 (0.38) SLC6A2MKNK1MAPK14IMPDH2TSPO
SCHEMBL21885332 0.91 TSPO (0.38) TSPOHSD17B1HSD17B2
SCHEMBL21885050 0.90 TSPO (0.38) TSPOHSD17B1HSD17B2
SCHEMBL21885049 0.90 TSPO (0.38) TSPOHSD17B1HSD17B2
SCHEMBL21885335 0.89 TSPO (0.34) MAPK14TSPO
SCHEMBL21885260 0.86 TSPO (0.38) TSPO
SCHEMBL21885090 0.86 TSPO (0.35) TSPOHSD17B1HSD17B2
SCHEMBL21885038 0.86 TSPO (0.35) TSPOHSD17B1HSD17B2
SCHEMBL21885333 0.85 TSPO (0.38) TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11737355-B2 Organic electroluminescence device and amine compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-22 US disclosed
US-11737355-B2 Organic electroluminescence device and amine compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-22 US disclosed
US-20200106022-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND AMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-04-02 US disclosed
EP-3628673-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND AMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE Samsung Display Co., Ltd. (KR) 2020-04-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200106022-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND AMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE MAOA, PNMT, TPH1 SLC6A2 178/4885MKNK1 3894/4885MAPK14 2051/4885
US-11737355-B2 Organic electroluminescence device and amine compound for organic electroluminescence device MAOA, PNMT, TPH1 SLC6A2 178/4885MKNK1 3894/4885MAPK14 2051/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.