SCHEMBL2188527

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9610679	0.89	CREBBP (0.51)	NOS1NOS3NOS2TSHRKMT2A
	SCHEMBL29114117	0.85	NOS3 (0.54)	NOS1NOS3NOS2LMNACYP1A2
	SCHEMBL30613110	0.85	NOS3 (0.54)	NOS1NOS3NOS2LMNACYP1A2
	SCHEMBL3633406	0.81	NOS1 (0.51)	NOS1NOS3NOS2LMNACYP1A2
	SCHEMBL3634731	0.80	NOS1 (0.51)	NOS1NOS3NOS2LMNACYP1A2
	SCHEMBL9610687	0.76	NOS1 (0.45)	NOS1NOS3NOS2TSHRKMT2A
	SCHEMBL18256100	0.76	KDM4E (0.51)	NPSR1KMT2AATMELANEKDM4E
	SCHEMBL244237	0.76	NOS1 (0.61)	NOS1NOS3NOS2LMNACYP1A2
	SCHEMBL29447076	0.76	NOS1 (0.61)	NOS1NOS3NOS2LMNACYP1A2
	SCHEMBL15488614	0.75	KMT2A (0.49)	NOS1NOS3NOS2LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.