Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 7/20 | 0.56 |
| ▸ | MMP2 | P08253 | 7/20 | 0.54 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.54 |
| ▸ | MMP3 | P08254 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29831835 | 1.00 | TDP1 (0.58) | TDP1MMP9MMP2ADAMTS4MMP3 | |
| SCHEMBL16058523 | 1.00 | TDP1 (0.58) | TDP1MMP9MMP2ADAMTS4MMP3 | |
| SCHEMBL697476 | 0.82 | MMP2 (0.79) | TDP1MMP9MMP2ADAMTS4MMP3 | |
| SCHEMBL1203540 | 0.82 | MMP2 (0.79) | TDP1MMP9MMP2ADAMTS4MMP3 | |
| SCHEMBL697477 | 0.82 | MMP2 (0.79) | TDP1MMP9MMP2ADAMTS4MMP3 | |
| Hydrochloric Acid SCHEMBL11133046 | 0.81 | MMP2 (0.77) | TDP1MMP9MMP2ADAMTS4MMP3 | |
| Hydrochloric Acid SCHEMBL3839410 | 0.81 | MMP2 (0.77) | TDP1MMP9MMP2ADAMTS4MMP3 | |
| SCHEMBL7879499 | 0.80 | TDP1 (0.55) | TDP1MMP9MMP2ADAMTS4MMP3 | |
| Chloromethane SCHEMBL7649372 | 0.80 | MMP2 (0.75) | TDP1MMP9MMP2ADAMTS4MMP3 | |
| Hydrochloric Acid SCHEMBL28872216 | 0.80 | MMP2 (0.75) | TDP1MMP9MMP2ADAMTS4MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109369635-B | Compound or pharmaceutically acceptable salt thereof, application thereof and pharmaceutical composition | 赛克里翁治疗有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-109384778-B | Use of a compound or a pharmaceutically acceptable salt thereof for the manufacture of a medicament for the treatment of a disease, health condition or disorder | 赛克里翁治疗有限公司 | 2022-12-13 | — | — | CN | disclosed |
| CN-110016020-B | Compound or pharmaceutically acceptable salt thereof, application and pharmaceutical composition thereof | 赛克里翁治疗有限公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-108912111-B | Compounds and pharmaceutical compositions | 赛克里翁治疗有限公司 | 2021-09-14 | — | — | CN | disclosed |
| US-10639308-B2 | sGC stimulators | CYCLERION THERAPEUTICS, INC. (US) | 2020-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10639308-B2 | sGC stimulators | PTGIS, CGAS, GUCY1A1 | TDP1 711/4885MMP9 4402/4885MMP2 3522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.