Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 11/20 | 0.79 |
| ▸ | MMP9 | P14780 | 10/20 | 0.79 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | MMP3 | P08254 | 2/20 | 0.70 |
| ▸ | MMP13 | P45452 | 2/20 | 0.70 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.70 |
| ▸ | MMP1 | P03956 | 1/20 | 0.70 |
| ▸ | MMP7 | P09237 | 1/20 | 0.70 |
| ▸ | CTSL | P07711 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697477 | 1.00 | MMP2 (0.79) | MMP2MMP9ADAMTS4TDP1ALDH1A1 | |
| SCHEMBL697476 | 1.00 | MMP2 (0.79) | MMP2MMP9ADAMTS4TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3839410 | 0.99 | MMP2 (0.77) | MMP2MMP9ADAMTS4TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11133046 | 0.99 | MMP2 (0.77) | MMP2MMP9ADAMTS4TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28872216 | 0.97 | MMP2 (0.75) | MMP2MMP9ADAMTS4TDP1ALDH1A1 | |
| Chloromethane SCHEMBL7649372 | 0.97 | MMP2 (0.75) | MMP2MMP9ADAMTS4TDP1ALDH1A1 | |
| SCHEMBL3856155 | 0.96 | MMP2 (0.73) | MMP2MMP9ADAMTS4TDP1ALDH1A1 | |
| SCHEMBL561565 | 0.95 | MMP2 (0.71) | MMP2MMP9ADAMTS4TDP1ALDH1A1 | |
| SCHEMBL433897 | 0.95 | MMP2 (0.71) | MMP2MMP9ADAMTS4TDP1ALDH1A1 | |
| SCHEMBL8063645 | 0.94 | TDP1 (0.78) | MMP2MMP9ADAMTS4TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115058-B2 | Process of preparation of optically active αaminoacetals | WEYLCHEM LAMOTTE S.A.S. (FR) | 2015-08-25 | — | — | US | claimed |
| EP-2245000-B1 | PROCESS OF PREPARATION OF OPTICALLY ACTIVE ALPHA AMINOACETALS | CLARIANT SPECIALTY FINE CHEM F (FR) | 2013-01-02 | — | — | EP | claimed |
| US-20110034726-A1 | Process Of Preparation Of Optically Active Alpha Aminoacetals | CLARIANT SPECIALTY FINE CHEMICALS (FRANCE) (FR) | 2011-02-10 | — | — | US | claimed |
| EP-2245000-A1 | PROCESS OF PREPARATION OF OPTICALLY ACTIVE ALPHA AMINOACETALS | Clariant Specialty Fine Chemicals (France) (FR) | 2010-11-03 | — | — | EP | claimed |
| WO-2009106386-A1 | PROCESS OF PREPARATION OF OPTICALLY ACTIVE ALPHA AMINOACETALS | CLARIANT SPECIALTY FINE CHEMICALS (FRANCE) (FR) | 2009-09-03 | — | — | WO | claimed |
| US-9115058-B2 | Process of preparation of optically active αaminoacetals | WEYLCHEM LAMOTTE S.A.S. (FR) | 2015-08-25 | — | — | US | disclosed |
| EP-2245000-B1 | PROCESS OF PREPARATION OF OPTICALLY ACTIVE ALPHA AMINOACETALS | CLARIANT SPECIALTY FINE CHEM F (FR) | 2013-01-02 | — | — | EP | disclosed |
| US-20110034726-A1 | Process Of Preparation Of Optically Active Alpha Aminoacetals | CLARIANT SPECIALTY FINE CHEMICALS (FRANCE) (FR) | 2011-02-10 | — | — | US | disclosed |
| EP-1513814-B1 | NOVEL PIPERIDINE COMPOUND | MITSUBISHI TANABE PHARMA CORP (JP) | 2010-03-17 | — | — | EP | disclosed |
| US-7619092-B2 | Piperidine compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-11-17 | — | — | US | disclosed |
| US-20090198052-A1 | METHOD FOR PREPARING OPTICALLY ACTIVE PIPERIDINE COMPOUNDS | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-08-06 | — | — | US | disclosed |
| EP-2022782-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE PIPERIDINE COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2009-02-11 | — | — | EP | disclosed |
| US-20030195159-A1 | HIV protease inhibitors based on amino acid derivatives | TAIMED BIOLOGICS, INC. (TW) | 2003-10-16 | — | — | US | disclosed |
| US-6610689-B2 | Viricides | PHARMACOR INC. (CA) | 2003-08-26 | — | — | US | disclosed |
| US-6608100-B1 | N-epsilon-amino acid substituted L-lysine sulfonamide derivatives possessing aspartyl protease inhibitory properties | PHARMACOR INC. (CA) | 2003-08-19 | — | — | US | disclosed |
| US-20030144265-A1 | HIV protease inhibitors based on amino acid derivatives | TAIMED BIOLOGICS, INC. (TW) | 2003-07-31 | — | — | US | disclosed |
| US-20030119803-A1 | HIV protease inhibitors based on amino acid derivatives | TAIMED BIOLOGICS, INC. (TW) | 2003-06-26 | — | — | US | disclosed |
| US-6506786-B2 | Such as N-isobutyl-N-(4-methylbenzene-sulfonyl)-N-(N-(4-methylbenzenesulfonyl)-L -phenylalanyl)-L-lysine | PHARMACOR INC. (CA) | 2003-01-14 | — | — | US | disclosed |
| US-20020151546-A1 | HIV protease inhibitors based on amino acid derivatives | TAIMED BIOLOGICS, INC. (TW) | 2002-10-17 | — | — | US | disclosed |
| WO-2002064551-A1 | HIV PROTEASE INHIBITORS BASED ON AMINO ACID DERIVATIVES | PHARMACOR INC. (CA) | 2002-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144265-A1 | HIV protease inhibitors based on amino acid derivatives | ANPEP, PEPD, XPNPEP1 | MMP2 845/4885MMP9 732/4885ADAMTS4 4020/4885 |
| US-20020151546-A1 | HIV protease inhibitors based on amino acid derivatives | ANPEP, PEPD, XPNPEP1 | MMP2 845/4885MMP9 732/4885ADAMTS4 4020/4885 |
| US-20030195159-A1 | HIV protease inhibitors based on amino acid derivatives | ANPEP, PEPD, XPNPEP1 | MMP2 845/4885MMP9 732/4885ADAMTS4 4020/4885 |
| US-20090198052-A1 | METHOD FOR PREPARING OPTICALLY ACTIVE PIPERIDINE COMPOUNDS | SNCA, SYNJ1, KCNH2 | MMP2 2580/4885MMP9 2726/4885ADAMTS4 4696/4885 |
| US-20110034726-A1 | Process Of Preparation Of Optically Active Alpha Aminoacetals | ALDH7A1, AADAT, ALAD | MMP2 3032/4885MMP9 3391/4885ADAMTS4 4377/4885 |
| US-20030119803-A1 | HIV protease inhibitors based on amino acid derivatives | ANPEP, PEPD, XPNPEP1 | MMP2 845/4885MMP9 732/4885ADAMTS4 4020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.