Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | KLK1 | P06870 | 1/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21884608 | 0.83 | FABP4 (0.40) | PPIAF10KLK1KLK5PLAU | |
| SCHEMBL21884595 | 0.77 | FABP4 (0.39) | PPIAF10PLAUPLAT | |
| SCHEMBL21884597 | 0.74 | ALDH1A1 (0.37) | PPIAF10PLAUPLATCNR2 | |
| SCHEMBL21884672 | 0.68 | AR (0.41) | PPIANPC1CRHBPRAB9ACRHR2 | |
| SCHEMBL21884590 | 0.67 | AR (0.46) | PPIAPLAUPLATCNR2P2RX1 | |
| SCHEMBL7110738 | 0.67 | ALOX15 (0.48) | — | |
| SCHEMBL21884635 | 0.66 | AR (0.44) | PPIANPC1RAB9A | |
| SCHEMBL21884520 | 0.65 | AR (0.35) | CNR2 | |
| Hydrochloric Acid SCHEMBL7110823 | 0.65 | ALOX15 (0.46) | — | |
| SCHEMBL21884599 | 0.64 | HSD17B1 (0.35) | F10PLAUPLATP2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020061473-A1 | SMALL MOLECULES TARGETING MUTANT MAMMALIAN PROTEINS | JNANA THERAPEUTICS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |