Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | RET | P07949 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8607746 | 0.80 | TSHR (0.72) | LMNATSHRTP53RETALOX12 | |
| 3-Methyl-2-Phenyl-4H-Chromen-4-One SCHEMBL694139 | 0.80 | ALDH1A1 (0.68) | LMNATSHRTP53RETALOX12 | |
| SCHEMBL27406417 | 0.77 | DDR2 (0.58) | LMNATSHRTP53RETALOX12 | |
| SCHEMBL311968 | 0.77 | CYP3A4 (0.72) | LMNATSHRTP53RETALOX12 | |
| SCHEMBL10022780 | 0.76 | TNKS (0.57) | LMNATSHRTP53RETALOX12 | |
| SCHEMBL27404210 | 0.75 | ABCG2 (0.76) | LMNATSHRTP53ALDH1A1CYP3A4 | |
| SCHEMBL311257 | 0.74 | CYP3A4 (0.62) | LMNATSHRTP53RETALOX12 | |
| SCHEMBL10800708 | 0.71 | NTRK1 (0.53) | LMNATSHRTP53RETALOX12 | |
| SCHEMBL11497614 | 0.70 | PTPN1 (0.39) | KMT2AKCNH2PTPN1MAPT | |
| SCHEMBL30637631 | 0.69 | ALDH1A1 (0.54) | LMNATSHRTP53HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020052774-A1 | FLAVONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2020-03-19 | — | — | WO | disclosed |