SCHEMBL311257

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL311868	0.83	CYP3A4 (0.68)	CYP3A4MEN1KMT2AHSD17B10MAPK1
	SCHEMBL312370	0.82	CYP3A4 (0.67)	CYP3A4MEN1KMT2AHSD17B10MAPK1
	SCHEMBL311942	0.80	ALDH1A1 (0.63)	CYP3A4MEN1KMT2AHSD17B10MAPK1
	SCHEMBL311349	0.79	CYP3A4 (0.62)	CYP3A4MEN1KMT2AHSD17B10MAPK1
	Hydrochloric Acid SCHEMBL312145	0.78	CYP3A4 (0.60)	CYP3A4MEN1KMT2AHSD17B10MAPK1
	SCHEMBL345696	0.77	MEN1 (1.00)	CYP3A4MEN1KMT2AHSD17B10MAPK1
	SCHEMBL28339226	0.75	KMT2A (0.55)	CYP3A4MEN1KMT2AHSD17B10MAPK1
	SCHEMBL311968	0.75	CYP3A4 (0.72)	CYP3A4MEN1KMT2AHSD17B10MAPK1
	SCHEMBL21886515	0.74	LMNA (0.49)	CYP3A4MEN1KMT2AHSD17B10MAPK1
	SCHEMBL15231797	0.74	KDM4E (0.62)	CYP3A4MEN1KMT2AHSD17B10MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.