Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 13/20 | 0.42 |
| ▸ | WNT3A | P56704 | 11/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30563103 | 0.89 | GNG2 (0.40) | CTNNB1WNT3AHPGD | |
| SCHEMBL829418 | 0.89 | GNG2 (0.40) | CTNNB1WNT3AHPGD | |
| SCHEMBL14357334 | 0.85 | ATM (0.50) | CTNNB1WNT3AHPGDTSHR | |
| SCHEMBL27636279 | 0.84 | ATM (0.36) | CTNNB1WNT3AHPGDSLC6A4PTGS1 | |
| SCHEMBL960318 | 0.82 | MAPT (0.46) | HPGDTSHR | |
| SCHEMBL14898029 | 0.80 | RXRA (0.50) | TSHR | |
| SCHEMBL925100 | 0.80 | KMT2A (0.36) | CTNNB1WNT3AHPGDPKMTSHR | |
| SCHEMBL27617374 | 0.79 | KMT2A (0.38) | HPGDTSHR | |
| SCHEMBL14898177 | 0.78 | CA12 (0.45) | HPGDTSHR | |
| SCHEMBL22763935 | 0.78 | RAB9A (0.44) | HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3201171-B1 | METHOD OF PREPARING INTERMEDIATE OF SALMETEROL | AMPHASTAR NANJING PHARMACEUTICALS INC (CN) | 2020-04-15 | — | — | EP | disclosed |