Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | CBX7 | O95931 | 2/20 | 0.38 |
| ▸ | CDYL2 | Q8N8U2 | 2/20 | 0.38 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.38 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22763956 | 0.84 | RAB9A (0.49) | RAB9ASMN1; SMN2TSHRCBX7CDYL2 | |
| SCHEMBL14357334 | 0.81 | ATM (0.50) | RAB9ASMN1; SMN2TSHRALDH1A1HPGD | |
| SCHEMBL27636279 | 0.80 | ATM (0.36) | SMN1; SMN2TSHRALDH1A1HPGDKDM4E | |
| SCHEMBL829418 | 0.80 | GNG2 (0.40) | ALDH1A1HPGD | |
| SCHEMBL30563103 | 0.80 | GNG2 (0.40) | ALDH1A1HPGD | |
| SCHEMBL960318 | 0.78 | MAPT (0.46) | RAB9ATSHRALDH1A1HPGDNPC1 | |
| SCHEMBL21886542 | 0.78 | CTNNB1 (0.42) | TSHRHPGD | |
| SCHEMBL14898029 | 0.76 | RXRA (0.50) | RAB9ATSHRALDH1A1MAPK1KDM4E | |
| SCHEMBL925100 | 0.76 | KMT2A (0.36) | RAB9ASMN1; SMN2TSHRALDH1A1HPGD | |
| SCHEMBL22763936 | 0.75 | TSHR (0.34) | TSHRALDH1A1MAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11053227-B2 | Process for preparing intermediates for the synthesis of optically active beta-amino alcohols by enzymatic reduction and novel synthesis intermediates | OLON S.P.A. (IT) | 2021-07-06 | — | — | US | disclosed |
| US-20200385366-A1 | PROCESS FOR PREPARING INTERMEDIATES FOR THE SYNTHESIS OF OPTICALLY ACTIVE BETA-AMINO ALCOHOLS BY ENZYMATIC REDUCTION AND NOVEL SYNTHESIS INTERMEDIATES | OLON S.P.A. (IT) | 2020-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200385366-A1 | PROCESS FOR PREPARING INTERMEDIATES FOR THE SYNTHESIS OF OPTICALLY ACTIVE BETA-AMINO ALCOHOLS BY ENZYMATIC REDUCTION AND NOVEL SYNTHESIS INTERMEDIATES | ADH1A, ADH1C, ADH5 | RAB9A 3913/4885SMN1; SMN2 3396/4885TSHR 3858/4885 |
| US-11053227-B2 | Process for preparing intermediates for the synthesis of optically active beta-amino alcohols by enzymatic reduction and novel synthesis intermediates | ADH1A, ADH1C, ADH5 | RAB9A 3913/4885SMN1; SMN2 3396/4885TSHR 3858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.