Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 3/20 | 0.30 |
| ▸ | HTR2C | P28335 | 3/20 | 0.30 |
| ▸ | HTR2B | P41595 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28668402 | 0.83 | MAPT (0.48) | MAPTALDH1A1LMNAHPGD | |
| SCHEMBL29724092 | 0.83 | MAPT (0.48) | MAPTALDH1A1LMNAHPGD | |
| SCHEMBL28294663 | 0.82 | ALDH1A1 (0.47) | MAPTALDH1A1LMNAHPGDTSHR | |
| SCHEMBL29724110 | 0.82 | ALDH1A1 (0.47) | MAPTALDH1A1LMNAHPGDTSHR | |
| SCHEMBL8882927 | 0.78 | KDM4E (0.41) | MAPTALDH1A1LMNAHPGDTSHR | |
| SCHEMBL8883179 | 0.77 | AR (0.34) | NOTUM | |
| SCHEMBL24006333 | 0.76 | KMT2A (0.33) | NOTUMPRMT5WDR77MAPTALDH1A1 | |
| SCHEMBL8488373 | 0.76 | GPR174 (0.58) | MAPTALDH1A1LMNAHPGDTSHR | |
| SCHEMBL8312242 | 0.75 | RXRA (0.34) | NOTUMPRMT5WDR77HRH3 | |
| SCHEMBL21886547 | 0.75 | HSP90AA1 (0.32) | NOTUMPRMT5WDR77MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914401-A | Methods for the manufacture of quinolone carboxylic acids derivatives and intermediates thereof | APOTEX, INC. (CA) | 1999-06-22 | — | — | US | disclosed |
| WO-1993015084-A1 | NOVEL CEPHALOSPORIN COMPOUNDS | IL-DONG PHARM. CO., LTD. (KR) | 1993-08-05 | — | — | WO | disclosed |