Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPD | P32754 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25061759 | 0.83 | ADORA2B (0.38) | ALDH1A1SMN1; SMN2PLA2G7MAPTL3MBTL1 | |
| SCHEMBL5411006 | 0.78 | ALDH1A1 (0.56) | ALDH1A1PLA2G7MAPTL3MBTL1POLB | |
| SCHEMBL28869790 | 0.78 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2PLA2G7MAPTL3MBTL1 | |
| SCHEMBL91340 | 0.75 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2PLA2G7MAPTL3MBTL1 | |
| SCHEMBL20942675 | 0.75 | POLB (0.46) | ALDH1A1SMN1; SMN2MAPTL3MBTL1POLB | |
| SCHEMBL6394776 | 0.71 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2PLA2G7MAPTL3MBTL1 | |
| SCHEMBL22108536 | 0.70 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MAPTL3MBTL1HSD17B10 | |
| SCHEMBL11869258 | 0.70 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2PLA2G7MAPTL3MBTL1 | |
| SCHEMBL26202930 | 0.70 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2MAPTADORA2BGAA | |
| SCHEMBL24759399 | 0.69 | ADORA2B (0.37) | ALDH1A1PLA2G7MAPTL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11072585-B2 | Fluorinated lysyl oxidase-like 2 inhibitors and uses thereof | PHARMAKEA, INC. (US) | 2021-07-27 | — | — | US | disclosed |
| US-20200115341-A1 | FLUORINATED LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. | 2020-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200115341-A1 | FLUORINATED LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | LOXL2, LOXL1, LOX | ALDH1A1 1095/4885SMN1; SMN2 2346/4885PLA2G7 232/4885 |
| US-11072585-B2 | Fluorinated lysyl oxidase-like 2 inhibitors and uses thereof | LOXL2, LOXL1, LOX | ALDH1A1 1095/4885SMN1; SMN2 2346/4885PLA2G7 232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.