Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22983967 | 0.81 | ABL1 (0.37) | ABL1RIN1POLBRNASE1 | |
| SCHEMBL25512274 | 0.70 | POLB (0.42) | ABL1RIN1POLBRNASE1 | |
| SCHEMBL25504697 | 0.68 | POLB (0.46) | ABL1RIN1POLBRNASE1 | |
| SCHEMBL21886710 | 0.68 | POLB (0.52) | ABL1RIN1POLBRNASE1 | |
| SCHEMBL25504696 | 0.68 | POLB (0.46) | ABL1RIN1POLBRNASE1 | |
| SCHEMBL5953531 | 0.68 | POLB (0.52) | ABL1RIN1POLBRNASE1 | |
| SCHEMBL6466613 | 0.68 | POLB (0.52) | ABL1RIN1POLBRNASE1 | |
| SCHEMBL22992440 | 0.68 | ABL1 (0.42) | ABL1RIN1POLB | |
| SCHEMBL26455083 | 0.67 | ABL1 (0.42) | ABL1RIN1POLBRNASE1 | |
| SCHEMBL8585251 | 0.65 | POLB (0.41) | ABL1RIN1POLBRNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021030763-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2021-02-18 | — | — | WO | disclosed |
| WO-2020072991-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2020-04-09 | — | — | WO | disclosed |