Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | HTR5A | P47898 | 2/20 | 0.31 |
| ▸ | KIF11 | P52732 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21887930 | 0.91 | LMNA (0.45) | LMNAESR1ESR2MAPTMEN1 | |
| SCHEMBL31757120 | 0.88 | ESR1 (0.44) | LMNAESR1ESR2MAPTMEN1 | |
| SCHEMBL31757119 | 0.88 | ESR1 (0.46) | LMNAESR1ESR2MAPTMEN1 | |
| SCHEMBL19764683 | 0.81 | ESR1 (0.40) | LMNAESR1ESR2MAPTMEN1 | |
| SCHEMBL19764661 | 0.81 | ESR1 (0.40) | LMNAESR1ESR2MAPTMEN1 | |
| SCHEMBL21887912 | 0.81 | POLB (0.44) | LMNAESR1ESR2MAPTMEN1 | |
| SCHEMBL24328671 | 0.80 | ESR1 (0.42) | LMNAESR1ESR2MAPTMEN1 | |
| SCHEMBL23335626 | 0.78 | LMNA (0.41) | LMNAESR1ESR2MAPTMEN1 | |
| SCHEMBL25937157 | 0.78 | LMNA (0.52) | LMNAESR1ESR2MAPTMEN1 | |
| SCHEMBL21585374 | 0.77 | PDK2 (0.40) | LMNAESR1ESR2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020056859-A1 | 9,10-DIHYDROACRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 宁波卢米蓝新材料有限公司 | 2020-03-26 | — | — | WO | disclosed |
| US-20200091436-A1 | 9,10-DIHYDRO-ACRIDINE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF | NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) | 2020-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200091436-A1 | 9,10-DIHYDRO-ACRIDINE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF | DHODH, DHRS9, QDPR | LMNA 1105/4885ESR1 433/4885ESR2 535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.