Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | MLNR | O43193 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21887915 | 0.81 | LMNA (0.45) | ESR1ESR2MEN1KMT2AKDM4E | |
| SCHEMBL23697042 | 0.81 | KDM4E (0.34) | ESR1ESR2MEN1KMT2AKDM4E | |
| SCHEMBL19764661 | 0.80 | ESR1 (0.40) | ESR1ESR2MEN1KMT2AKDM4E | |
| SCHEMBL24328671 | 0.79 | ESR1 (0.42) | ESR1ESR2MEN1KMT2AKDM4E | |
| SCHEMBL23696698 | 0.78 | PDK2 (0.31) | — | |
| SCHEMBL16787322 | 0.78 | PDK2 (0.34) | — | |
| SCHEMBL28267231 | 0.78 | NOX1 (0.41) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL22639818 | 0.77 | ESR1 (0.36) | ESR1ESR2MEN1KMT2AKDM4E | |
| SCHEMBL25937157 | 0.77 | LMNA (0.52) | ESR1ESR2MEN1KMT2AKDM4E | |
| SCHEMBL23125637 | 0.77 | PGR (0.32) | MEN1KMT2APGRADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10566547-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2020-02-18 | — | — | US | disclosed |
| US-20180013074-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2018-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10566547-B2 | Organic electroluminescent materials and devices | PAX2, EYA2, NLRP1 | ESR1 523/4885ESR2 243/4885MEN1 2810/4885 |
| US-20180013074-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | PAX2, EYA2, NLRP1 | ESR1 523/4885ESR2 243/4885MEN1 2810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.