Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | HRH2 | P25021 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24199566 | 0.84 | TSHR (0.36) | TSHRKCNA5KCNH2SLC6A2SLC6A4 | |
| SCHEMBL22725661 | 0.74 | TSHR (0.38) | TSHRKCNA5KCNH2SLC6A2SLC6A4 | |
| SCHEMBL20757741 | 0.72 | SLC6A3 (0.45) | TSHRSLC6A3 | |
| SCHEMBL26278070 | 0.71 | ESR1 (0.45) | TSHRKCNA5KCNH2SLC6A2SLC6A4 | |
| SCHEMBL29750645 | 0.71 | L3MBTL1 (0.41) | TSHRKCNA5KCNH2SLC6A2SLC6A4 | |
| SCHEMBL3249970 | 0.70 | MAOA (0.50) | TSHRKCNA5KCNH2SLC6A2SLC6A4 | |
| SCHEMBL25003875 | 0.70 | TSHR (0.41) | TSHRKCNA5KCNH2SLC6A2SLC6A4 | |
| SCHEMBL21703726 | 0.70 | TSHR (0.37) | TSHRKCNA5KCNH2SLC6A2SLC6A4 | |
| SCHEMBL20375684 | 0.70 | KCNA5 (0.39) | TSHRKCNA5KCNH2HRH3CYP2D6 | |
| SCHEMBL20385424 | 0.69 | ESR1 (0.46) | TSHRKCNA5KCNH2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200085053-A1 | THIOBENZOIMIDAZOLE AS FUNGICIDES | REDAG CROP PROT LTD (GB) | 2020-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200085053-A1 | THIOBENZOIMIDAZOLE AS FUNGICIDES | CYP1B1, CYP51A1, CYP1A2 | TSHR 979/4885KCNA5 689/4885KCNH2 935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.