Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9008779 | 0.79 | THRB (0.42) | THRBTSHRALDH1A1CA1CA2 | |
| SCHEMBL13567318 | 0.77 | THRB (0.40) | THRBTSHRALDH1A1CA1CA2 | |
| SCHEMBL5074348 | 0.74 | ALDH1A1 (0.47) | THRBTSHRALDH1A1 | |
| SCHEMBL14885808 | 0.74 | THRB (0.38) | THRBTSHRALDH1A1CA1CA2 | |
| SCHEMBL11530639 | 0.68 | THRB (0.46) | THRBTSHRALDH1A1CA1CA2 | |
| SCHEMBL67638 | 0.68 | TSHR (0.39) | TSHRALDH1A1 | |
| SCHEMBL8854706 | 0.68 | TSHR (0.39) | TSHRALDH1A1 | |
| SCHEMBL15636 | 0.68 | THRB (0.74) | THRBTSHRALDH1A1CA1CA2 | |
| SCHEMBL6142874 | 0.68 | THRB (0.74) | THRBTSHRALDH1A1CA1CA2 | |
| SCHEMBL16404807 | 0.67 | THRB (0.57) | THRBTSHRALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052481-B1 | USE OF POLYMERIZABLE STABLE RADICALS FOR REDUCING THE SHRINKAGE STRESS OF DENTAL COMPOSITIONS | DENTSPLY SIRONA INC (US) | 2020-04-08 | — | — | EP | disclosed |