SCHEMBL21890971

SCHEMBL21890971

c1ccc(-c2ccc3nc(-c4cccc(-c5cccc6c5sc5c(-c7nc(-c8ccccc8)nc(-c8ccccc8)n7)cccc56)c4)oc3c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VSIR Q9H7M9 6/20 0.44
ESR1 P03372 2/20 0.40
ESR2 Q92731 2/20 0.40
KDM4E B2RXH2 2/20 0.40
NPC1 O15118 2/20 0.40
ALDH1A1 P00352 2/20 0.40
MAPT P10636 2/20 0.40
HPGD P15428 2/20 0.40
RAB9A P51151 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
GPR119 Q8TDV5 9/20 0.39
PDCD1 Q15116 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.38
GAA P10253 1/20 0.38
NFKB1 P19838 1/20 0.38
STAT1 P42224 1/20 0.38
GFER P55789 1/20 0.38
NFKB2 Q00653 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25459696 0.94 VSIR (0.44) VSIRESR1ESR2KDM4ENPC1
SCHEMBL21890974 0.92 ESR1 (0.44) VSIRESR1ESR2KDM4EALDH1A1
SCHEMBL21890976 0.92 HPSE (0.46) KDM4ENPC1ALDH1A1MAPTHPGD
SCHEMBL25459644 0.90 NPC1 (0.44) VSIRESR1ESR2KDM4ENPC1
SCHEMBL25459695 0.88 ALOX5 (0.46) VSIRESR1ESR2KDM4ENPC1
SCHEMBL22736080 0.88 VSIR (0.42) VSIRESR1ESR2KDM4ENPC1
SCHEMBL21890973 0.86 VSIR (0.39) VSIRKDM4ENPC1HPGDRAB9A
SCHEMBL23473731 0.86 GPR119 (0.42) VSIRESR1ESR2KDM4ENPC1
SCHEMBL22736767 0.86 VSIR (0.39) VSIRESR1ESR2KDM4ENPC1
SCHEMBL22736765 0.86 VSIR (0.39) VSIRESR1ESR2KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020071863-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME 주식회사 엘지화학 2020-04-09 WO disclosed