Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21891750 | 0.94 | SIRT1 (0.43) | SIRT1CYP1A2SIRT2FAAHNPC1 | |
| SCHEMBL21891795 | 0.83 | FAAH (0.43) | SIRT1CYP1A2FAAHNPC1RAB9A | |
| SCHEMBL21891818 | 0.83 | SIRT1 (0.52) | SIRT1SIRT2FAAH | |
| SCHEMBL21891798 | 0.82 | FAAH (0.56) | SIRT1CYP1A2SIRT2FAAHHPGD | |
| SCHEMBL23130277 | 0.82 | SIRT1 (0.56) | SIRT1SIRT2FAAH | |
| SCHEMBL21802411 | 0.82 | SIRT1 (0.56) | SIRT1SIRT2FAAH | |
| SCHEMBL21891762 | 0.81 | POLB (0.45) | SIRT1CYP1A2SIRT2NPC1RAB9A | |
| SCHEMBL23423232 | 0.81 | POLB (0.45) | SIRT1CYP1A2SIRT2NPC1RAB9A | |
| SCHEMBL23515282 | 0.80 | FAAH (0.40) | SIRT1CYP1A2FAAHNPC1RAB9A | |
| SCHEMBL21891776 | 0.79 | CTSK (0.45) | SIRT1CYP1A2NPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10968168-B2 | Isocyanate production method | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2021-04-06 | — | — | US | disclosed |
| US-20200115327-A1 | ISOCYANATE PRODUCTION METHOD | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2020-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200115327-A1 | ISOCYANATE PRODUCTION METHOD | IDH3A, ALKBH3, CPS1 | SIRT1 1448/4885CYP1A2 184/4885SIRT2 861/4885 |
| US-10968168-B2 | Isocyanate production method | IDH3A, ALKBH3, CPS1 | SIRT1 1448/4885CYP1A2 184/4885SIRT2 861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.