Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 10/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21893086 | 1.00 | ENPP2 (0.43) | ENPP2LPAR2FAAHTRPV1TERT | |
| SCHEMBL24300519 | 1.00 | ENPP2 (0.43) | ENPP2LPAR2FAAHTRPV1TERT | |
| SCHEMBL18561758 | 1.00 | ENPP2 (0.43) | ENPP2LPAR2FAAHTRPV1TERT | |
| SCHEMBL4980864 | 0.88 | MAPT (0.44) | FAAHTRPV1TERTGMNNUSP2 | |
| SCHEMBL28075413 | 0.87 | ALDH1A1 (0.41) | — | |
| SCHEMBL15070944 | 0.81 | MAPT (0.46) | TRPV1LMNAMAPTALOX15HSD17B10 | |
| SCHEMBL18019085 | 0.78 | ALDH1A1 (0.42) | LMNAMAPTALOX15RECQLBLM | |
| SCHEMBL18548543 | 0.78 | ENPP2 (0.60) | ENPP2LPAR2 | |
| SCHEMBL18548545 | 0.78 | ENPP2 (0.60) | ENPP2LPAR2 | |
| SCHEMBL22804723 | 0.77 | FAAH (0.50) | FAAHTRPV1TERTGMNNUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3623364-A1 | PRODRUG COMPOUNDS AND THEIR USES | Ligand Pharmaceuticals, Inc. (US) | 2020-03-18 | — | — | EP | disclosed |