Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20578066 | 0.91 | LMNA (0.73) | LMNAALDH1A1POLBL3MBTL1HPGD | |
| SCHEMBL1471641 | 0.81 | LMNA (0.66) | LMNAALDH1A1POLBL3MBTL1HPGD | |
| SCHEMBL20578208 | 0.81 | LMNA (0.85) | LMNAALDH1A1POLBL3MBTL1HPGD | |
| SCHEMBL8752473 | 0.81 | HPGD (0.81) | LMNAALDH1A1POLBL3MBTL1HPGD | |
| SCHEMBL2239360 | 0.79 | HPGD (0.74) | LMNAALDH1A1POLBL3MBTL1HPGD | |
| SCHEMBL5955364 | 0.79 | LMNA (0.66) | LMNAALDH1A1POLBL3MBTL1HPGD | |
| SCHEMBL23014068 | 0.79 | ALDH1A1 (0.67) | LMNAALDH1A1POLBL3MBTL1HPGD | |
| SCHEMBL28841731 | 0.76 | KEAP1 (0.79) | LMNAALDH1A1POLBL3MBTL1HPGD | |
| SCHEMBL13265810 | 0.74 | MAPT (0.51) | LMNAALDH1A1POLBL3MBTL1HPGD | |
| SCHEMBL20578056 | 0.74 | LMNA (0.71) | LMNAALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795144-B2 | Inhibitors of RAC1 and uses thereof for treating cancers | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-10-24 | — | — | US | disclosed |
| US-20200095199-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS | NANTES UNIVERSITE (FR) | 2020-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11795144-B2 | Inhibitors of RAC1 and uses thereof for treating cancers | RAC1, KRAS, CYRIB | LMNA 3861/4885ALDH1A1 2069/4885POLB 2799/4885 |
| US-20200095199-A1 | INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS | RAC1, KRAS, CYRIB | LMNA 3861/4885ALDH1A1 2069/4885POLB 2799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.