Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21358993 | 0.84 | KLKB1 (0.34) | KDM4EPOLBKLKB1SMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL21355066 | 0.83 | KLKB1 (0.34) | KDM4EPOLBKLKB1SMN1; SMN2NPC1 | |
| SCHEMBL20713625 | 0.81 | GABRA1 (0.42) | KLKB1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL22278022 | 0.78 | POLB (0.31) | POLBMAPT | |
| SCHEMBL17815221 | 0.77 | CCR1 (0.37) | KDM4EPOLBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL21355405 | 0.77 | KLKB1 (0.49) | KDM4EPOLBKLKB1TDP1ALDH1A1 | |
| SCHEMBL11155397 | 0.74 | DRD4 (0.40) | KDM4EPOLBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL20116289 | 0.74 | CCR1 (0.34) | KDM4EPOLBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL24657617 | 0.71 | TP53 (0.33) | KDM4ESMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL20116290 | 0.71 | TP53 (0.33) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065613-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |