Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 14/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21893561 | 0.88 | MGLL (0.42) | MGLLP2RX7 | |
| SCHEMBL21893843 | 0.83 | MGLL (0.50) | MGLLP2RX7 | |
| SCHEMBL21893646 | 0.83 | P2RX7 (0.41) | MGLLP2RX7 | |
| SCHEMBL21893627 | 0.83 | P2RX7 (0.46) | MGLLP2RX7 | |
| SCHEMBL21893565 | 0.83 | MGLL (0.41) | MGLLP2RX7 | |
| SCHEMBL21893586 | 0.82 | MGLL (0.58) | MGLLP2RX7 | |
| SCHEMBL21894523 | 0.81 | P2RX7 (0.47) | MGLLP2RX7 | |
| SCHEMBL21893506 | 0.81 | MGLL (0.59) | MGLLP2RX7 | |
| SCHEMBL21893719 | 0.80 | KDM1A (0.44) | MGLLP2RX7 | |
| SCHEMBL21893537 | 0.80 | P2RX7 (0.50) | MGLLP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065613-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |
| US-20160237072-A1 | OXAZOLIDINONES AS MODULATORS OF MGLUR5 | BRISTOL MYERS SQUIBB CO (US) | 2016-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160237072-A1 | OXAZOLIDINONES AS MODULATORS OF MGLUR5 | GRM5, GRIK5, GRM1 | MGLL 1520/4885P2RX7 331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.