Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.59 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.48 |
| ▸ | BRD4 | O60885 | 3/20 | 0.46 |
| ▸ | CDK4 | P11802 | 3/20 | 0.42 |
| ▸ | CCND1 | P24385 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21893530 | 0.87 | P2RX7 (0.47) | MGLLP2RX7CREBBPBRD4 | |
| SCHEMBL21893775 | 0.87 | P2RX7 (0.48) | MGLLP2RX7CREBBPBRD4 | |
| SCHEMBL21893968 | 0.86 | P2RX7 (0.47) | MGLLP2RX7CREBBPBRD4CDK4 | |
| SCHEMBL21893971 | 0.84 | MGLL (0.60) | MGLLP2RX7 | |
| SCHEMBL21893602 | 0.83 | MGLL (0.58) | MGLLP2RX7 | |
| SCHEMBL21893595 | 0.83 | P2RX7 (0.48) | MGLLP2RX7CREBBPBRD4 | |
| SCHEMBL21893593 | 0.83 | MGLL (0.58) | MGLLP2RX7CDK4CCND1 | |
| SCHEMBL21818338 | 0.81 | MGLL (0.64) | MGLLCREBBP | |
| SCHEMBL32682503 | 0.81 | MGLL (0.64) | MGLLCREBBP | |
| SCHEMBL21893719 | 0.80 | KDM1A (0.44) | MGLLP2RX7CREBBPBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065613-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |