Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5081325 | 0.80 | ALDH1A1 (0.33) | GRM8GRM4TSHR | |
| SCHEMBL11977475 | 0.74 | L3MBTL1 (0.32) | — | |
| SCHEMBL2889732 | 0.69 | — | — | |
| SCHEMBL20121971 | 0.68 | MITF (0.32) | — | |
| SCHEMBL254677 | 0.68 | TDP1 (0.50) | — | |
| SCHEMBL14576550 | 0.68 | SLC6A4 (0.33) | — | |
| SCHEMBL2307925 | 0.68 | — | — | |
| SCHEMBL18265509 | 0.65 | SLC6A4 (0.35) | — | |
| SCHEMBL24654960 | 0.64 | GAA (0.42) | GAA | |
| SCHEMBL1602688 | 0.64 | SLC6A4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110272400-B | Synthesis method of 2-trifluoromethyl substituted furan compound and derivative thereof | 福州大学 | 2022-08-23 | — | — | CN | disclosed |
| WO-2020065613-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |
| CN-110272400-A | The synthetic method of 2- trifluoromethyl substituted furan compound and its derivative | 福州大学 | 2019-09-24 | — | — | CN | disclosed |