Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.41 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7189747 | 0.84 | ALDH1A1 (0.57) | ALDH1A1VCAM1TTRKDM4EPTGS2 | |
| SCHEMBL939715 | 0.82 | ALDH1A1 (0.55) | ALDH1A1VCAM1KDM4EPTGS2RAB9A | |
| SCHEMBL6212368 | 0.82 | ALDH1A1 (0.55) | ALDH1A1VCAM1KDM4EPTGS2RAB9A | |
| SCHEMBL10389237 | 0.82 | ALDH1A1 (0.55) | ALDH1A1VCAM1TTRKDM4EPTGS2 | |
| SCHEMBL17577404 | 0.82 | TRPV4 (0.41) | ALDH1A1VCAM1KDM4ETRPV4MEN1 | |
| SCHEMBL11528923 | 0.81 | ALDH1A1 (0.53) | ALDH1A1VCAM1TTRKDM4EPTGS2 | |
| Water SCHEMBL10948493 | 0.81 | ALDH1A1 (0.53) | ALDH1A1VCAM1TTRKDM4EPTGS2 | |
| SCHEMBL11528928 | 0.81 | ALDH1A1 (0.53) | ALDH1A1VCAM1TTRKDM4EPTGS2 | |
| SCHEMBL10816998 | 0.78 | PTGS2 (0.61) | ALDH1A1TTRKDM4EPTGS2RAB9A | |
| SCHEMBL198172 | 0.74 | MCL1 (0.55) | ALDH1A1KDM4ETRPV4TSHRMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11339138-B2 | Process and intermediates for the preparation of certain nematicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2022-05-24 | — | — | US | disclosed |
| US-20210309621-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF CERTAIN NEMATICIDAL SULFONAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2021-10-07 | — | — | US | disclosed |
| WO-2020072616-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF CERTAIN NEMATICIDAL SULFONAMIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2020-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210309621-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF CERTAIN NEMATICIDAL SULFONAMIDES | C1S, CBR3, C5 | ALDH1A1 3871/4885VCAM1 4885/4885TTR 4506/4885 |
| US-11339138-B2 | Process and intermediates for the preparation of certain nematicidal sulfonamides | C1S, CBR3, C5 | ALDH1A1 3871/4885VCAM1 4885/4885TTR 4506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.