SCHEMBL21895700

Nc1nc2c(ncn2[C@@H]2O[C@H](OP(=O)(O)S)CC2OP(=O)(S)OC[C@H]2O[C@@H](n3c(=O)[nH]c4c(N)ncnc43)C[C@@H]2O)c(=O)[nH]1

nearest known ligand 0.52

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	POLB	P06746	2/20	0.52

▸	P2RY2	P41231	1/20	0.48

▸	P2RY4	P51582	1/20	0.48

▸	P2RY6	Q15077	1/20	0.48

▸	DTYMK	P23919	4/20	0.47

▸	FUT5	Q11128	1/20	0.46

▸	NT5E	P21589	1/20	0.45

▸	F2	P00734	2/20	0.44

▸	TERT	O14746	1/20	0.43

▸	TGM2	P21980	1/20	0.42

▸	ENPP1	P22413	1/20	0.41

▸	P2RY1	P47900	1/20	0.41

▸	KRAS	P01116	3/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL23679594	0.85	POLB (0.53)	POLBP2RY2P2RY4P2RY6DTYMK
SCHEMBL18521732	0.81	POLB (0.58)	POLBP2RY2P2RY4P2RY6DTYMK
SCHEMBL22072422	0.81	POLB (0.58)	POLBP2RY2P2RY4P2RY6DTYMK
SCHEMBL18521731	0.81	POLB (0.58)	POLBP2RY2P2RY4P2RY6DTYMK
SCHEMBL22434625	0.80	POLB (0.62)	POLBP2RY2P2RY4P2RY6DTYMK
SCHEMBL23679552	0.80	DTYMK (0.42)	P2RY2DTYMKP2RY1
SCHEMBL23679569	0.79	POLB (0.49)	POLBDTYMKENPP1P2RY1
SCHEMBL13359725	0.78	POLB (0.61)	POLBP2RY2P2RY4P2RY6DTYMK
SCHEMBL14389876	0.78	POLB (0.61)	POLBP2RY2P2RY4P2RY6DTYMK
SCHEMBL21896066	0.78	POLB (0.53)	POLBP2RY2DTYMKNT5ETERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2020057546-A1	CYCLIC DINUCLEOTIDE ANALOGUE, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION	上海迪诺医药科技有限公司	2020-03-26	—	—	WO	disclosed