Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20128803 | 0.97 | GPR119 (0.34) | GPR119 | |
| SCHEMBL9611090 | 0.93 | GPR119 (0.33) | GPR119ALDH1A1 | |
| SCHEMBL9611086 | 0.85 | KCNH2 (0.32) | — | |
| SCHEMBL15383298 | 0.85 | ALDH1A1 (0.38) | GPR119ALDH1A1SIGMAR1 | |
| SCHEMBL23664757 | 0.80 | GBA2 (0.40) | GPR119 | |
| SCHEMBL19852059 | 0.80 | SIGMAR1 (0.47) | SIGMAR1 | |
| SCHEMBL21104963 | 0.80 | SIGMAR1 (0.47) | SIGMAR1 | |
| SCHEMBL15383215 | 0.79 | ALDH1A1 (0.44) | ALDH1A1SIGMAR1 | |
| SCHEMBL27013526 | 0.78 | GNAO1 (0.44) | ALDH1A1 | |
| SCHEMBL21152372 | 0.77 | CYP1A2 (0.46) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200121684-A1 | MODULATORS OF BTK PROTEOLYSIS AND METHODS OF USE | UNIV YALE (US) | 2020-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200121684-A1 | MODULATORS OF BTK PROTEOLYSIS AND METHODS OF USE | BTK, CBL, CRBN | GPR119 4272/4885ALDH1A1 4291/4885SIGMAR1 4432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.