Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 10/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5100424 | 1.00 | PTGIR (0.46) | PTGIRCASRCA2HTR1A | |
| SCHEMBL730472 | 0.83 | PTGIR (0.46) | PTGIRCA2 | |
| SCHEMBL9455313 | 0.83 | GRM2 (0.49) | CASRHTR1A | |
| SCHEMBL14367854 | 0.81 | CASR (0.47) | PTGIRCASRHTR1A | |
| SCHEMBL14367871 | 0.81 | CASR (0.47) | PTGIRCASRHTR1A | |
| SCHEMBL14463199 | 0.81 | PTGIR (0.35) | PTGIR | |
| SCHEMBL1545420 | 0.78 | CA2 (0.55) | CA2 | |
| SCHEMBL7982000 | 0.78 | CA2 (0.55) | CA2 | |
| SCHEMBL2544576 | 0.78 | CA2 (0.55) | CA2 | |
| SCHEMBL31343616 | 0.76 | GRM2 (0.52) | PTGIRCASRCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1486491-B1 | CARBOXYLIC ACID COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2011-07-13 | — | — | EP | disclosed |
| US-7351705-B2 | Carboxylic acid compounds and a pharmaceutical agent comprising the compound as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-04-01 | — | — | US | disclosed |
| US-7291644-B2 | Indole derivatives | ONO PHARMACEUTICALS CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |
| US-7291644-B2 | Indole derivatives | ONO PHARMACEUTICALS CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |
| US-7291644-B2 | Indole derivatives | ONO PHARMACEUTICALS CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |
| US-7135495-B2 | Indole derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-11-14 | — | — | US | disclosed |
| US-20060194864-A1 | Indole derivatives | ONO PHARMACEUTICAL CO., LTD. | 2006-08-31 | — | — | US | disclosed |
| US-20050222216-A1 | Carboxyoic acid compounds and drugs containing the compounds as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-10-06 | — | — | US | disclosed |
| US-20050004097-A1 | Indole derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
| EP-1486491-A1 | CARBOXYOIC ACID COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-12-15 | — | — | EP | disclosed |
| EP-1424335-A1 | INDOLE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-06-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194864-A1 | Indole derivatives | IDO1, IDO2, PTGIR | PTGIR 3/4885CASR 611/4885CA2 2700/4885 |
| US-20050004097-A1 | Indole derivatives | IDO1, IDO2, PTGIR | PTGIR 3/4885CASR 611/4885CA2 2700/4885 |
| US-20050222216-A1 | Carboxyoic acid compounds and drugs containing the compounds as the active ingredient | UACA, CPA3, HCAR1 | PTGIR 30/4885CASR 231/4885CA2 190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.