Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7692886 | 0.83 | LMNA (0.42) | PLAULMNASMN1; SMN2TSHRCYP2C9 | |
| SCHEMBL18784152 | 0.80 | PLAU (0.46) | PLAULMNASMN1; SMN2TSHRCYP2C9 | |
| SCHEMBL28002539 | 0.77 | L3MBTL1 (0.44) | PLAULMNASMN1; SMN2TSHRCYP2C9 | |
| SCHEMBL3580724 | 0.76 | L3MBTL1 (0.43) | PLAULMNASMN1; SMN2TSHRCYP2C9 | |
| SCHEMBL287761 | 0.76 | LMNA (0.47) | PLAULMNASMN1; SMN2TSHRCYP2C9 | |
| SCHEMBL27417430 | 0.75 | PLAU (0.42) | PLAULMNASMN1; SMN2TSHRCYP2C9 | |
| SCHEMBL23413510 | 0.74 | LMNA (0.46) | PLAULMNASMN1; SMN2TSHRCYP2C9 | |
| Hydrochloric Acid SCHEMBL20139726 | 0.74 | LMNA (0.46) | PLAULMNASMN1; SMN2TSHRCYP2C9 | |
| SCHEMBL2760820 | 0.74 | PLAU (0.48) | PLAULMNASMN1; SMN2TSHRCYP2C9 | |
| SCHEMBL30143410 | 0.74 | PLAU (0.48) | PLAULMNASMN1; SMN2TSHRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200138028-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200138028-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | PRF1, NOX1, ARG1 | PLAU 4673/4885LMNA 4450/4885SMN1; SMN2 3056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.