SCHEMBL219055

SCHEMBL219055

C=C(C)C(=O)NCc1ccc(N(C)C)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
KDM4E B2RXH2 3/20 0.55
HTT P42858 1/20 0.55
HDAC1 Q13547 8/20 0.52
HDAC6 Q9UBN7 7/20 0.52
HDAC2 Q92769 6/20 0.52
HDAC10 Q969S8 6/20 0.52
HDAC8 Q9BY41 6/20 0.52
MEN1 O00255 1/20 0.50
USP2 O75604 1/20 0.50
RECQL P46063 1/20 0.50
KMT2A Q03164 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CA2 P00918 1/20 0.49
HDAC3 O15379 5/20 0.48
HDAC4 P56524 5/20 0.48
HDAC7 Q8WUI4 5/20 0.48
HDAC11 Q96DB2 5/20 0.48
HDAC9 Q9UKV0 5/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL731190 0.88 KMT2A (0.50) ALDH1A1HTTHDAC1HDAC6MEN1
SCHEMBL222075 0.84 ALDH1A1 (0.50) ALDH1A1MEN1KMT2ATDP1L3MBTL1
SCHEMBL9242992 0.82 ALDH1A1 (0.61) ALDH1A1KDM4EHTTHDAC1HDAC6
SCHEMBL222008 0.81 ESRRG (0.50) ALDH1A1KDM4EHTTMEN1KMT2A
SCHEMBL5024307 0.81 SMN1; SMN2 (0.56) ALDH1A1KDM4EMEN1KMT2AL3MBTL1
SCHEMBL3869761 0.81 KDM4E (0.53) ALDH1A1KDM4EHTTHDAC1HDAC6
SCHEMBL6415716 0.79 EPHX2 (0.50) ALDH1A1HTTHDAC1HDAC6KMT2A
SCHEMBL202718 0.79 MEN1 (0.61) ALDH1A1KDM4EMEN1KMT2AGAA
SCHEMBL19215206 0.79 CYP4F2 (0.47) ALDH1A1HTTHDAC1HDAC6MEN1
SCHEMBL222320 0.79 EGFR (0.44) ALDH1A1HDAC1HDAC6HDAC2HDAC10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10222721-B2 Urethane foam and toner-conveying roller using the same BRIDGESTONE CORPORATION (JP) 2019-03-05 US disclosed
US-9316958-B2 Charge-controlled polyurethane foam and toner-conveying roller using the same BRIDGESTONE CORPORATION (JP) 2016-04-19 US disclosed
US-8088876-B2 Copolymer, resin for electrophotographic functional component parts, developing roller, and electrophotographic apparatus CANON KASEI KABUSHIKI KAISHA (JP) 2012-01-03 US disclosed
US-20110188900-A1 URETHANE FOAM AND TONER-CONVEYING ROLLER USING THE SAME BRIDGESTONE CORPORATION (JP) 2011-08-04 US disclosed
US-20110177926-A1 CHARGE-CONTROLLED POLYURETHANE FOAM AND TONER-CONVEYING ROLLER USING THE SAME BRIDGESTONE CORPORATION (JP) 2011-07-21 US disclosed