SCHEMBL222320

SCHEMBL222320

C=C(C)C(=O)NCc1ccc(N(CCCC)CCCC)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.44
ERBB2 P04626 1/20 0.44
CNR2 P34972 3/20 0.43
HDAC6 Q9UBN7 4/20 0.43
HDAC1 Q13547 4/20 0.43
ESRRG P62508 2/20 0.42
HPGD P15428 2/20 0.40
ALDH1A1 P00352 2/20 0.40
THRA P10827 1/20 0.40
THRB P10828 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
MEN1 O00255 1/20 0.39
LMNA P02545 1/20 0.39
MAPK1 P28482 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL222008 0.92 ESRRG (0.50) EGFRERBB2CNR2ESRRGALDH1A1
SCHEMBL222075 0.85 ALDH1A1 (0.50) CNR2ESRRGALDH1A1MEN1LMNA
SCHEMBL1262787 0.81 TGM2 (0.54) EGFRERBB2CNR2HDAC6HDAC1
SCHEMBL731190 0.80 KMT2A (0.50) HDAC6HDAC1ALDH1A1MEN1KMT2A
SCHEMBL219055 0.79 ALDH1A1 (0.55) HDAC6HDAC1ALDH1A1CA2MEN1
SCHEMBL26217887 0.76 ESRRG (0.45) EGFRERBB2CNR2ESRRGALDH1A1
SCHEMBL8077288 0.75 TSHR (0.43) EGFRERBB2CNR2ESRRGHPGD
SCHEMBL219072 0.74 HDAC3 (0.48) HDAC1HPGDTHRATHRBHDAC3
SCHEMBL221394 0.74 HDAC3 (0.48) HDAC1HPGDTHRATHRBHDAC3
SCHEMBL3869761 0.74 KDM4E (0.53) EGFRERBB2CNR2HDAC6HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10222721-B2 Urethane foam and toner-conveying roller using the same BRIDGESTONE CORPORATION (JP) 2019-03-05 US disclosed
US-9563154-B2 Toner transfer roller and image forming device using the same BRIDGESTONE CORPORATION (JP) 2017-02-07 US disclosed
US-9316958-B2 Charge-controlled polyurethane foam and toner-conveying roller using the same BRIDGESTONE CORPORATION (JP) 2016-04-19 US disclosed
US-8088876-B2 Copolymer, resin for electrophotographic functional component parts, developing roller, and electrophotographic apparatus CANON KASEI KABUSHIKI KAISHA (JP) 2012-01-03 US disclosed
US-20110188900-A1 URETHANE FOAM AND TONER-CONVEYING ROLLER USING THE SAME BRIDGESTONE CORPORATION (JP) 2011-08-04 US disclosed
US-20110177926-A1 CHARGE-CONTROLLED POLYURETHANE FOAM AND TONER-CONVEYING ROLLER USING THE SAME BRIDGESTONE CORPORATION (JP) 2011-07-21 US disclosed
US-20100158579-A1 TONER TRANSFER ROLLER AND IMAGE FORMING DEVICE USING THE SAME BRIDGESTONE CORPORATION (JP) 2010-06-24 US disclosed